In the 37th year of the reign of Emperor Jiajing of the Ming Dynasty, the eunuchs were in power. In order to curry favor with the head of the factory, the master of alchemy proposed to use the "live tiger heart" to make an elixir for "reinvigorating yang and rebirth". Therefore, the East Factory set up a "Sili Hunting Ground" in a small town on the southwestern border where tigers live, to hunt tigers for refining. However, it was unexpected that this move caused a strange virus to enter the tiger's body, making it crazy and causing a plague to spread rapidly...