The highly respected priest Sang-hyun (Song Kang-ho) participated in a secret vaccine medical experiment in Africa and was transfused with blood of unknown origin, which turned him into a vampire both psychologically and physically. He fell in love with his friend Kang-woo's (Shin Ha-kyun) wife Tae-joo (Kim Ok-bin), and their illicit love dragged him into an irreversible situation.