As a new deadly plague approaches, Gus (Christian Convery) and his fellow hybrids are held captive by General Albert (Neil Sandilands) and the Last Man. Hoping to consolidate his power by finding a cure, Albert uses the children as experimental bait to capture Dr. Aditya Singh (Adeel Akhtar), who is trying to save his infected wife Rani (Arissa Virani). To protect his friend, Gus agrees to help Dr. Singh and embarks on an unknown journey to explore his origins and the role his mother, Birdie (Amy Seimetz), played in the events of The Collapse. Outside the Sanctuary, Tommy Jeppard (Nonso Anoz) and Amy Eden (Dania Ramirez) team up to free the hybrids, and their partnership will be tested as Jeppard's secret comes to light. As events from the past threaten the present rescue effort, Gus and his reunited family come into conflict with Albert and the evil forces that want to destroy them once and for all. SweetTooth: The Boy with Antlers is based on the DC Comics book series by Jeff Lemire and is executive produced by Jim Mickle, Susan Downey, Robert Downey Jr., Amanda Burrell and Linda Moran. The series is produced by Warner Bros. Television.